The Red Devils captain was forced to sit out Thursday’s FA Cup tie with Derby County after enduring difficulty in training.

Manchester United manager Ole Gunnar Solskjaer has implied that Harry Maguire could miss Sunday’s Premier League fixture against Manchester City Because of an ankle injury.

The England centre-back, who has made 39 appearances in all competitions since joining from Leicester City last summer, was left from Thursday’s FA Cup fifth-round clash with Derby County after hurting himself in training.

And Solskjaer confirmed that he is a doubt for the derby meeting with their regional rivals at Old Trafford at the weekend.

“I had a word with him before training yesterday to say I am not going to break him,” Solskjaer told MUTV when asked why Maguire was missing from the team to face Phillip Cocu’s side.

“But then he rolled his ankle in training so he had to remain at home. Hopefully, he will be fine for the weekend but I am not sure.”

Maguire, who turned 27 on the day of the Derby clash, took to Twitter to express his disappointment at being forced to miss the experience with the Championship side and expects to be back shortly.

“Disappointed to miss out through injury,” he Tweeted. “Working hard for it ASAP. Great luck to the lads.”

Victor Lindelof and Eric Bailly began at the heart of the Red Devils defence against Derby as Solskjaer made six changes to his team.

Aaron Wan-Bissaka and Daniel James will also be at risk of missing the Manchester derby, and Solskjaer urged the rest of the squad to step up and submit a claim for a spot in Sunday’s starting 11.

“Well the players are desperate to play and we wanted to give them a chance. There are a few injuries and they could not have played anyway. But we have chosen a strong team and we can go through,” he added.

“There are two or three players that are getting the opportunity to stake a claim for the derby because I am not positive if Harry, Dan or Aaron will be accessible. So there are opportunities [tonight] for a few.”

United are currently fifth in the Premier League – 15 points behind second-placed Town and a further 22 adrift of leaders Liverpool.